Rasburicase 1.5 Mg Injection

Rasburicase 1.5 Mg Injection Specification

Life Span
24 months from date of manufacture

Pacakaging (Quantity Per Box)
1 vial per box

Origin of Medicine
India

Indication
Tumor lysis syndrome-induced hyperuricemia

Dosage Form
Liquid injection

Brand Name
Rasburicase

Packaging Type
Vial

Salt Composition
Rasburicase 1.5 mg

Drug Type
Biological product

Ingredients
Rasburicase

Physical Form
Injection

Function
Reduces uric acid levels in blood

Recommended For
Adults and children with hyperuricemia associated with malignancy

Dosage
1.5 mg per vial, as directed by physician

Dosage Guidelines
Administered intravenously under medical supervision

Storage Instructions
Store in a refrigerator (2C-8C). Do not freeze.

Prescription Required
Yes

Shelf Life After Reconstitution
Use within 24 hours when stored at 2C-8C

Side Effects
Nausea, vomiting, fever, headache, hypersensitivity reactions

Marketed By
Leading pharmaceutical companies in India

Color
Colorless to slightly yellow solution

Contraindications
G6PD deficiency, hypersensitivity to rasburicase

Animal Origin
No

Administration Route
Intravenous infusion

Registration Status
Approved by Drug Controller General of India (DCGI)

Reconstitution
Requires dilution with sterile water for injection

Rasburicase 1.5 Mg Injection Trade Information

Minimum Order Quantity
10 Pieces

Supply Ability
1000 Pieces Per Month

Delivery Time
7 Days

About Rasburicase 1.5 Mg Injection

Strength	1.5 mg
Dosage Form	Injection
Brand	Rasburnat
Packaging Type	Box
Manufactured By	Natco
Treatment	Prevention and treatment of tumor lysis syndrome

Rasburnat Injection is used in the treatment of high uric acid due to chemotherapy. It lowers uric acid levels in the blood which helps prevent kidney damage in cancer patients.

It is given as a slow injection into veins by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include nausea, headache, vomiting, and rash. However, some side effects require immediate action, hence inform your doctor if you experience difficulty in breathing, chest pain, swelling in the face and throat, itching, or dizziness after taking this medicine. Your doctor may get regular blood tests to check the levels of uric acid during treatment with this medicine. It is better to take plenty of fluids to avoid dehydration.

Inform your doctor if you are pregnant, planning pregnancy or breastfeeding. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using.

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Innovative Therapy for Hyperuricemia in Cancer Patients

Rasburicase Injection offers a crucial intervention for patients at risk of tumor lysis syndrome, a common complication in aggressive cancer treatments. By converting uric acid into a more soluble compound, this medication promptly lowers blood uric acid levels, reducing the risk of acute kidney injury. Suitable for both adults and children, it is delivered via intravenous infusion in a hospital or clinical setting under medical supervision.

Proper Administration and Handling Guidelines

Before administration, Rasburicase 1.5 mg must be reconstituted with sterile water for injection and further diluted as per the physician's instructions. The injection is given directly into the vein over a prescribed duration, ensuring optimal drug efficacy. The reconstituted solution should be stored between 2C-8C and used within 24 hours. Only trained healthcare providers should handle its preparation and delivery.

FAQ's of Rasburicase 1.5 Mg Injection:

Q: How should Rasburicase 1.5 mg Injection be administered?

A: Rasburicase 1.5 mg Injection is administered as an intravenous infusion after reconstituting the vial with sterile water and further dilution as instructed by a healthcare provider. It must be given under the supervision of a qualified medical professional in a hospital or clinic.

Q: What is Rasburicase used for, and who can benefit from it?

A: Rasburicase is indicated for managing hyperuricemia associated with malignancy, particularly in cases of tumor lysis syndrome. Both adults and pediatric patients with elevated uric acid levels due to cancer treatment may benefit from its use.

Q: When is Rasburicase contraindicated?

A: Rasburicase is contraindicated in individuals with glucose-6-phosphate dehydrogenase (G6PD) deficiency and those with known hypersensitivity to rasburicase or any of its components.

Q: Where should Rasburicase Injection be stored?

A: Unopened and reconstituted Rasburicase Injection vials must be stored in a refrigerator at 2C-8C. The reconstituted solution should be used within 24 hours and must not be frozen.

Q: What is the process for preparing Rasburicase Injection for use?

A: The vial should be reconstituted with sterile water for injection and then diluted further before intravenous administration as per physician's guidelines. Only trained medical staff should handle the preparation and administration.

Q: What side effects may occur with Rasburicase?

A: Common side effects include nausea, vomiting, headache, fever, and hypersensitivity reactions. Patients should be monitored closely by healthcare personnel during and after administration.

Q: What are the benefits of using Rasburicase for tumor lysis syndrome?

A: Rasburicase rapidly lowers dangerously high uric acid levels, reducing the likelihood of kidney damage and improving patient outcomes during intensive cancer therapy.